Ecosystem

These are the organizations, programs, and pieces of infrastructure we think the field needs and doesn't yet have. If you currently work on or are interested in working on one of these topics, we would love to hear from you.

What's missing Who's building

Pillar

Type

24 gaps across 8 priorities

Nucleic Acid Synthesis ScreeningPrevent5 gaps

Know Your Customer (KYC)Prevent1 gap

AI-Bio SafeguardsPrevent3 gaps

Research GovernancePrevent3 gaps

Threat Disruption, Attribution & DeterrencePrevent3 gaps

Built Environment BiohardeningDefend1 gap

Rapid Medical CountermeasuresDefend3 gaps

Global Response CoordinationDefend5 gaps

Ecosystem

Split-order detection organization — cross-provider system to detect split orders across synthesis firms

A verification authority for synthesis screening

Function-based screening providers — next-generation screening that detects dangerous function, not just known sequences

Independent auditor/verification bodies for synthesis screening compliance

Benchtop Device Security Consortium — industry body to enforce screening safeguards on desktop synthesis devices

Harmonized KYC infrastructure for high-risk bio

Secure Biological Data Stewardship Organization — trusted infrastructure for hosting high-risk biological training data

A monitoring layer for AI-Bio misuse

Guardian model development — continuous real-time AI monitoring layer for frontier biological AI deployments

Bio-audit provider — independent third-party biosafety and biosecurity verification for high-risk labs

A bio-audit body for high-consequence research

China and international advocacy coalition for biosecurity standards adoption globally

Red teaming organization — dedicated adversarial testing of misuse safeguards across synthesis, KYC, and AI

A disruption capability for biological threats

Split-order screening and clearinghouse organization for cross-provider threat signal aggregation

Biohardening for critical built environments

A rapid-MCM platform with a real activation plan

"Blueprint Bio" for countermeasures and diagnostics — regranting and coordination for MCM development

Standing clinical trials network for pandemic response — pre-positioned sites ready for rapid Phase 1+2 trials

A standing public-private response coordination body

International pandemic response coordination center

Public trust and communications preparedness organization

501(c)(4) advocacy and lobbying organization focused on biosecurity policy

Independent communications shop for biosecurity policy and response