The 5-Year Plan

The plan unfolds in phases: foundation, implementation, scale, readiness, and durable defensive advantage. This ambitious roadmap is intended to define priorities, motivate action and accelerate progress.

2027
Build the foundation
2028
Pilots into operating systems
2029
Scale and enforce
2030
Achieve durable readiness
2031
Maintain defensive advantage

2027

Year One

Build the foundation

2027 is the year to establish the legal, institutional, and technical foundation of the plan. The highest-leverage, and most readily actionable interventions must move from concept to implementation. By year-end, they must be underway: legislation introduced or advancing, standards drafted, pilots launched, commitments secured, and coordination mechanisms operating.

Prevent $120MDetect $50MRespond $210M
$380M
Suggested spend
Cumulative · $380M

2028

Year Two

Pilots into operating systems

2028 is the year the plan must move beyond promising starts. Systems launched in 2027 must become real operating capabilities: the goal is to move from standards to adoption, from pilots to functioning workflows, and from commitments to routine practice.

Prevent $130MDetect $65MRespond $285M
$480M
Suggested spend
Cumulative · $860M

2029

Year Three

Scale and enforce

2029 is the scale year. Voluntary systems must become enforceable; local systems must become international; we need to turn promising pilots into durable preparedness infrastructure.

Prevent $115MDetect $80MRespond $400M
$595M
Suggested spend
Cumulative · $1.455B

2030

Year Four

Achieve durable readiness

2030 is the year of readiness. The right ideas are in motion and the system must be made to actually work under stress.

Prevent $90MDetect $75MRespond $500M
$665M
Suggested spend
Cumulative · $2.12B

2031

Year Five

Maintain defensive advantage

The purpose of these first five years is to establish a durable global biodefense architecture that continues to improve over time.

Prevent $45MDetect $55MRespond $380M
$480M
Suggested spend
Cumulative · $2.6B